Warshadaha quruxda waxay ku dadaalayeen sidii ay u qancin lahaayeen rabitaanka haweenka ee ah inay u ekaadaan da 'weyn.Sanadihii la soo dhaafay, peptides firfircoon ee firfircoon ayaa si weyn loogu isticmaalay warshadaha qurxinta.Waqtigan xaadirka ah, ku dhawaad 50 nooc oo alaabta ceeriin ah ayaa soo saaray warshado caan ah oo la isku qurxiyo oo dibadda ah.Sababtoo ah kakanaanta sababaha gabowga, noocyada kala duwan ee peptides quruxda ayaa door gaar ah ka ciyaara habab kala duwan si loo gaaro ujeedada ka hortagga laalaabka.Maanta, aynu eegno noocyada kala duwan ee peptides iyo tirooyinka ku jira liiska walxaha.
Kala soocidda dhaqameedku waxay u qaybisay peptides bilicda hab farsamaysan peptides Signal, Neurotransmitter xannibaya peptides-ka, iyo peptides-ka-qaadan.
Mid.Calaamadaha peptides
Calaamadaha peptides waxay kor u qaadaan isku-dhafka borotiinka matrixka, gaar ahaan kolajka, waxayna sidoo kale kordhin kartaa wax soo saarka elastin, hyaluronic acid, glycosaminoglycans, iyo fibronectin.peptides-yadani waxay kor u qaadaan isku-dhafka kolajka iyagoo kordhinaya dhaqdhaqaaqa unugyada stromal, samaynta maqaarku mid aad u jilicsan oo dhalinyaro ah.Si la mid ah maaddooyinka laalaabka dhaqameed ee dhaqameed, sida fitamiin C, fitamiin A.Daraasadaha P&G waxay muujiyeen in palmitoyl pentapeptide-3 ay kor u qaaddo soosaarka kolajka iyo borotiinnada kale ee unugyada unugyada, oo ay ku jiraan elastin iyo fibronectin.Palmitoyl oligopeptides (palmitoyl tripeptide-1) waxay sameeyaan wax badan oo isku mid ah, taas oo ah sababta palmitoyl oligopeptides sida caadiga ah loo isticmaalo.Palmitoyl pentapeptide-3, palmitoyl tripeptide-1, palmitoyl hexapeptide, palmitoyl tripeptide-5, hexapeptide-9 iyo nutmeg pentapeptide-11, kuwaas oo inta badan lagu iibiyo suuqa, waa peptides signal.
Laba.Neurotransmitter peptides
Peptide-kani waa hannaan u eg botoxin.Waxay joojisaa isku-darka soo-dhoweynta SNARE, waxay joojisaa sii-deynta xad-dhaafka ah ee acetycholine maqaarka, gudaha waxay xannibaysaa macluumaadka murqaha gudbinta dareemayaasha, waxayna dejisaa muruqyada wajiga si ay u dejiso khadadka wanaagsan.peptides-kaan waxaa si weyn loogu isticmaalaa sida peptides-ka calaamadaha waxayna si gaar ah ugu habboon yihiin in loo isticmaalo meelaha murqaha hadalku ku urursan yihiin (geesaha indhaha, wejiga, iyo wejiga).Badeecadaha peptide-ka wakiil ka ah waa: acetyl hexapeptide-3, acetyl octapeptide-1, pentapeptide-3, dipeptide ophiotoxin iyo pentapeptide-3, kuwaas oo inta badan la isticmaalo waa acetyl hexapeptide-3.
Saddex.Peptides sidday
Trieptides (Gly-L-His-L-Lys(GHK)) ee ku jira balasmaha bini'aadamku waxay leeyihiin xidhiidh adag oo leh ions copper, kuwaas oo si iskiis ah u samayn kara peptide copper adag (GHK-Cu).Soosaarida naxaastu waa qayb muhiim u ah bogsashada dhaawaca iyo habab badan oo falcelin enzymatic ah.Daraasaduhu waxay muujiyeen in GHK-Cu ay kor u qaadi karto koritaanka, kala qaybinta iyo kala soocida unugyada dareemayaasha iyo unugyada difaaca jirka, waxayna si wax ku ool ah kor ugu qaadi kartaa bogsashada dhaawaca iyo koritaanka jeermiska.Alaabada uu matalo peptide copper waa peptide copper.
Afar.noocyada kale ee peptides
Shaqada guud ee peptides-dhaqameedku waa ka-hortagga laalaabka iyo gabowga ka-hortagga marka laga reebo peptide naxaas ah (peptide naxaas ah wuxuu leeyahay waxyaabo badan oo isku mid ah).Sanadihii la soo dhaafay, noocyada kala duwan ee peptides ayaa sii kordhayay, qaar ka mid ah kuwaas oo gaaraya ujeedada ka hortagga laalaabista iyo gabowga ka soo jeeda habka cusub iyo aragtida (oxidation oxidation-free-free oxidation, anti-carbonylation, anti-bararka, anti-bararka, anti-bararka). - bararka iyo kor u qaadida hagaajinta maqaarka).
1. Maqaarka ka-hortagga maqaarka, kor u adayga maqaarka
Palmitoyl dipeptide-5, hexapeptide-8, ama hexapeptide-10 waxay adkeeyaan maqaarka iyagoo kicinaya LamininV nooca IV iyo VII kolajka, halka palmitoyl tetrapeptide-7 ay yarayso soosaarka interleukin-6 waxayna yaraynaysaa bararka.Noocan ah peptide functional waa horumar aad u firfircoon, moodooyinka cusub ayaa si joogto ah u kordhaya, inta badan la isticmaalo waa timirta tetrapeptide-7.
2. Glycosylation
peptide-yadani waxay ka ilaalin karaan kolajka burburka iyo isku xidhka noocyada kala duwan ee carbonyl (RCS), halka qaar ka mid ah peptides-ka-carbonyl-ka-hortagga ah ay ka aargudan karaan xagjirrada xorta ah.Daryeel dhaqameedka maqaarka ayaa muhiimad weyn siiya xag-jirayaasha ka-hortagga xorta ah, oo si sii kordheysa u muuqda ka-hortagga-carbonylation.Carnosine, tripeptide-1 iyo dipeptide-4 waa peptides-ka leh hawlahan oo kale
3. Hagaajinta bararka indhaha, hagaajinta microcirculation iyo xoojinta wareegga dhiigga
Acetyltetrapeptide-5 iyo dipeptide-2 waa kuwa awood u leh ACE inhibitors kuwaas oo hagaajiya wareegga dhiigga iyaga oo joojinaya beddelka angiotensin I ee angiotensin II.
4. Kor u hagaajinta maqaarka
Palmitoyl hexapeptidde-6, oo ah qaab-dhismeedka difaaca hidaha ee peptide-ka, ayaa si wax ku ool ah u kicin kara fibroblast bararka iyo isku xirka, isku-dhafka kolajka iyo guuritaanka unugyada.
Peptides-ka ka-hortagga gabowga ee kore ayaa ku daray intooda badan.Marka laga soo tago peptides-ka ka hortagga gabowga ee aan kor ku soo xusnay, waxaa lagu soo saaray warshadaha waxyaabo kale oo badan oo la isku qurxiyo, sida caddeynta, xoojinta naasaha, miisaanka oo yaraada iyo wixii la mid ah.
Waqtiga boostada: Mar-22-2023