Waa maxay jihaynta peptides-ka macmalka ah ee la habeeyey?Qodobadan ma garanaysaa?

Isku-dubaridka silsiladda Peptide ayaa si weyn loogu isticmaalay dhinacyo badan, gaar ahaan horumarinta daroogada, cilmi-baarista bayoolajiga iyo bayoolojiyada.Peptides ee dhererka kala duwan iyo isku xigxiga ayaa lagu soo saari karaa iyada oo loo marayo isku-dhafka silsiladda peptide ee diyaarinta daroogada, side daroogada, falanqaynta borotiinka, cilmi-baarista shaqada iyo wixii la mid ah.Haddaba waa maxay jihada peptides synthetic?Maanta, Gutuo Xiaobian ayaa ku siin doona jawaab faahfaahsan hoos.

Waa maxay jihaynta peptides-ka macmalka ah ee la habeeyey?Ma garanaysaa qodobadan?

Isku dhafka silsiladda Peptide waxaa lagu gaari karaa iyadoo si tartiib tartiib ah loogu daro molecules amino acid silsiladda peptide ee jirta, taasoo dhalinaysa curaarta peptide cusub.Sababo la xiriira koritaanka ka N dhamaadka si silsilad C peptide, sidaas jihada synthesis ayaa sidoo kale ka N dhamaadka C. Tani waa sababta oo ah C terminal iyo N terminal amino acids inta u dhaxaysa habka formation bond peptide, acids amino ee dhamaadka karboxyl. (C) iyo amino (N) ee jira dhamaadka falcelinta silsiladda peptide, waxay keenaan curaarta cusub ee peptide.Marka, jihada isku-dhafka laga bilaabo N dhamaadka ilaa C.

Isku-dhafka Peptide wuxuu inta badan isku xiraa molecules amino acid iyadoo loo marayo habka kiimikaad si loo sameeyo habka peptides.Si gaar ah loo yeelo, isku-dhafka silsiladda polypeptide wuxuu isku xiraa molecules amino acid, markeeda, waxaa samayn kara curaarta kiimikada si loo dhiso habka peptides.Isku-dubaridka silsiladda Peptide waxaa caadi ahaan lagu fuliyaa hab-samaynta weji adag ama isku-dhafka dareeraha-wejiga ah.Isku-dubaridka wejiga adag, asiidhyada amino-yada bilawga ah waxay ku xidhan yihiin walxaha wejiga adag, ka dibna silsiladda peptide-ka ayaa si isku xigta loo kordhiyaa iyada oo si tartiib tartiib ah loogu daro asiidhyada amino ee shakhsi ahaaneed.

Xagga sare waa isku-dhafka yar-yar si loo soo bandhigo kala-soocidda peptide-ka iyo doorka aqoonta la xiriirta, tinto adag oo diiradda saareysa isku-dhafka peptide, muujinta borotiinka, diyaarinta antibody, iwm, waxay ku hawlan tahay warshadaha peptide sanado badan, tayada wax soo saarka heerka koowaad. , soo dhawoow tirada badan ee macaamiishu inay u yimaadaan inay la tashadaan.