Sunta abeesada

Jaantuska qaab dhismeedka ee serpentin-like venom peptide triplet:

Sunta abeesada

Heerarka falanqaynta,HPLC≥98%

Sunta abeesada

(2S) -beta-alanyl-L-prolyl-2,4-diamino-N- (phenylmethyl) butanamide acetate

Alias: (2S) -beta-alanyl-L-prolyl-2, 4-diamino-N -(benzyl) butyamido acetate;(2S) -beta-alanyl-L-prolyl-2,4-diamino-N- (phenylmethyl) butanamide acetate;SYN-AKE;mas-tripeptide;H – beta – Ala – Pro – Dab – NHBzl.2 koob;Mas tr

Lambarka CAS: 823202-99-9

Qaaciddada molecular: C19H29N5O3.2(C2H4O2)

Miisaanka molecular: 495.58

Hordhac:

Taxanaha: H-β-Ala-Pro-Dab-NH-Bzl

Muuqaal: budo cad

Nagu saabsan:

Sunta sida peptide-ka oo kale ah waa peptide yar oo u ekaysiiya hawsha sunta abeesada, halkii ay ka ahaan lahayd sunta abeesada, waa peptide firfircoon oo u eeg qaabka sunta abeesada.Sunta peptide ayaa shan jeer ka waxtar badan botulinum yaraynta laalaabkii, waxaana la ogaaday inay hoos u dhigtay laalaabkii 52 boqolkiiba 28 maalmood ka dib isticmaalka bini'aadamka.

Faa'iidooyinka

1. Laalaabkii ka hortagga iyo gabowga

2. Hagaajinta tayada maqaarka

3. Wajiga, qoorta iyo alaabta daryeelka gacmaha

4. Hagaaji qaabka maqaarka, ka dhig maqaarka mid siman oo jilicsan, kor u qaad midabka

5. Waxa ay geli kartaa lakabka qoto dheer ee maqaarka, buuxinta kolajka, oo ay tirtirto raadadkii ay ka tageen sannado

6. Ciyaar doorka qoyaanka iyo fuuq-celinta, ka dhig maqaarka mid adag oo siman, dhalaalaya oo qurux badan

7. Adkee laalaab ka-hortagga, dib u adkee wejiga qaabka V, oo soo celi maqaarka dhalinyarada

8. Ka hortag wax soo saarka melanin ee maqaarka

Doorka:

Dipeptide diamino-butadibenzyl amide diacetate / sunta sida tripeptide waa wax soo saar wax ku ool ah oo ka hortagga kireeynta firfircoon iyada oo dejinaysa muruqyada wajiga si waafaqsan Waglerin 1, xarunta xannibaadda neuromuscular ee venom Temple Viper.Trieptides sunta abeesada waxay ku dhaqmaan xuubabka postsynaptic waxayna yihiin antagonistayaasha la bedeli karo ee muruqa nicotinic acetylcholine reseptor (nmAChR).Sunta maska ​​ee tripeptide waxay ku xidhan tahay qaybta ε ee nmAChR waxayna xannibaysaa isku xidhka acetylcholine ee reseptor-ka, taasoo keentay xannibaadda soo-dhoweeyaha.Xaaladda xanniban, ions sodium lama la nuugi karo oo lama saari karo, gudbinta dareenka dareenka ayaa xannibay, sidaas darteed nasashada muruqa.