Dulaglutide,923950-08-7

Magac loo yaqaanulaglutide - xal ku jira PBS / dulaglutide

CAS No.:923950-08-7

Shirkadda No. :GT-F002

Taxanaha: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Glu-Gln-Ala-Ala-Lys-Glu-Phe-Ile- Ala-Trp-Leu-Val-Lys-Gly-Gl y-Gly-OH

Qaaciddada molecular: C149H221N37O49

Miisaanka molecular: 3314.62

Dulaglutide CAS NO.923950-08-7.jpg

Tilmaamayaasha farsamada:

Muuqaalka budada cad
Nadiifinta (HPLC) waxay ahayd ≥95.0%

Hal heterozygosity ayaa ka yar 2.0%

Waxyaabaha aysiidhku ku jirto waxay u dhaxaysay 5.0% ilaa 12.0%

Qoyaanku wuxuu ahaa ≤10.0%

Waxa ku jira peptide ≥80.0%

Baakaynta iyo Rarista:

Heerkul hoose, xirxiro faakuum, sax ah ilaa milligram marka la codsado.

Sharaxaada Alaabta:

Durraglutide waa GLP-1R agonist oo cusub oo muddo dheer shaqaynaysa, kaas oo ka yimid isku-dhafka laba DPP-4 inhibitory GLP-1 analogues iyo silsiladda culus ee immunoglobulin-ka IgG4-Fc.Dhaqdhaqaaqeeda waxay la mid tahay GLP-1 endogenous ee muujinta kiliinikada, oo leh nolol nus ah 5 maalmood, waxayna si wax ku ool ah dib u dhigi kartaa nadiifinta kelyaha.FDA waxay ogolaatay dulaglutide duridda subcutaneous bishii Sebtembar 2014. Komishanka Yurub wuxuu oggolaaday dulaglutide cirbadeynta subcutaneous ee Yurub Disembar 2014.

Kaydinta: Qaboji oo qallaji -20 ℃ kuna kaydi meel ka fog iftiinka

Xusuusin: Ujeeddooyin cilmi-baaris oo keliya, maaha maadooyinka aadanaha