Hordhac kooban oo ku saabsan tidulutide

Farsamaynta ficilka tidulutide Gattex (teduglutide)

Teduglutide waa analooga dabiiciga ah ee bini'aadamka ee glucagon-like peptide-2 (GLP-2), peptide oo ay soo saareen unugyada L ee mindhicirka fog.GLP-2 waxaa loo yaqaanaa inay hagaajiso qulqulka dhiigga ee mindhicirrada iyo portal waxayna joojisaa dheecaanka aashitada gastric.Heerarka lu peptide iyo peptide reseptor 2 glucagon, factor koritaanka insulin-sida unugyada endocrine mindhicirka, unugyada epithelial ee fiber muruqa, submucosa iyo myenteric u dhexeeya neurons mindhicirka.Dhaqdhaqaaqa soo-dhoweyntan ayaa sababa sii-deynta maxalliga ah ee warbaahinta kala duwan, oo ay ku jiraan factor koritaanka insulin-sida (IGF) 1, factor koritaanka unugyada formation nitrogen oxide iyo Cutin unugyada koritaanka factor (KGF).

Tidulutide, oo ah glucagon-sida peptide 2 (GLP-2) analooga, waxay yaraynaysaa faaruqinta caloosha iyo dheef-shiid kiimikaadka waxayna nidaamisaa koritaanka, taranka iyo soo kabashada unugyada xuubka mindhicirka.Peptide waxay kordhisay tirada guud ee unugyadaas, waxay kordhin kartaa nuugista xiidmaha yar, waxay yaraynaysaa shubanka.Cudurka mindhicirka gaaban ee dadka qaangaarka ah waxaa lagu daweyn karaa kiliinig.Daawadu waxay noqotay dawooyinka ugu horreeya ee lagula taliyay naadir laakiin aad u daciif ah.

Hordhac kooban oo ku saabsan tidulutide

Kiimikada molecular formula ee tidulutide

Halbeegyada aasaasiga ah

Magaca: c peptide (Teduglutide)

Lambarka: GT – F027

Lambarka CAS: 197922-42-2

Taxanaha: His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn- Trp-Leu-Ile-Gln-Thr-Lys- Ile-Thr-Asp

Qaaciddada molecular: C164H252N44O55S

Miisaanka molecular: 3752.08248